断奶前后仔猪和母猪粪便源大肠杆菌耐药性和铜抗性的分析

doi:10.11843/j.issn.0366-6964.2015.03.019

Abstract

Abstract:

The experiment was conducted to compare the difference of antibiotic and copper resistance among E.coli isolated from sows and piglets before and after weaning.In the experiment，224 of E.coil were isolated from lactation sows，suckling and weaned piglets，which antibiotic resistance to 7 antimicrobial agents and copper resistance was detected using agar dilution method according to the recommendation of the CLSI.The remarkable antibiotic resistance of isolated E.coil to 7 selected antibiotics was observed，the percentage of resistance isolates to individual antibiotic was ranged from 28.13% to 93.30%.70.09% of all isolates possessed multi-drug resistance (MDR).The antibiotic resistance of E.coil isolates from sows and piglets was highly similar，except resistance to ampicillin and gentamicin.However，the antibiotic resistance of isolates from weaned pigs changed significantly.The antibiotic resistance to ceftiofur，florfenicol and chloramphenicol increased very significantly (P<0.01)，resistance to ampicillin increased significantly (P<0.05).Comparing to sow and suckling piglets，the copper resistance of isolates from weaned pigs increased very significantly (P<0.01).In addition，when the copper resistance of E.coil isolates changed，the antibiotic resistance also changed，there might be a correlation between copper and antibiotic resistance.Drug-resistance bacteria in the gut of sows and in feed antibiotics contribute significantly to the development of antibiotics of E.coil in the gut of piglets.Moreover，it initially reveals the presence of a certain relationship between in feed copper and antibiotic resistance change of E.coil isolates form piglets.

CLC Number:

S852.6

JI Xu，ZHENG Wei-jiang，ZOU Xue-ting，HUANG Jiu-xi，YAO Wen. Analysis of Antibiotic and Copper Resistance of Escherichia coli Isolated from Feces of Sows and Piglets before and after Weaning[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2015, 46(3): 482-490.

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Analysis of Antibiotic and Copper Resistance of Escherichia coli Isolated from Feces of Sows and Piglets before and after Weaning

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